Human bcma uniprot
Web(ab263875) Human BCMA ELISA Kit Sign in or register to save this reagent to your favourites Supplier Abcam Kit Type ELISA Assay Type Sandwich (Quantitative) Detection Method Colorimetric Sensitivity 10.81 pg/ml Dynamic Range 18.75 pg/ml - 1200 pg/ml Target Tumor necrosis factor receptor superfamily member 17 UniProt Q02223 - … Web11 Sep 2007 · UniProt A7KBT6 · A7KBT6_HUMAN Protein B cell maturation antigen transcript variant 5 Gene BCMA Status UniProtKB unreviewed (TrEMBL) Organism …
Human bcma uniprot
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WebHomo sapiens (Human) Synonyms: BCM, BCMA. Uniprot: Q02223 go to UniProt. Biological function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK go to UniProt. WebRecombinant CHO-K1 cells constitutively expressing both the human BCMA protein (B-Cell Maturation Antigen or CD269, GenBank accession #NM_001192) and the Gaussia …
WebHowever, BCMA is highly expressed on multiple myeloma cells . CD16 is mainly expressed on NK cells and macrophages and is currently known to be one of the most potent activating receptors on NK cells. In this study, we constructed a two-arm IgG1-based human NK-cell engager, named BK1, against CD16A and BCMA. WebUniProt ID: Q02223 : Source: Purified from ascites. Species reactivity: Human : Crossreactivity: Does not cross-react with mouse BCMA. ... The extracellular domain of …
WebHuman Antibody Type Monoclonal Host Species Mouse Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) Preparation The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. Concentration WebBCMA (mouse):Fc (human) (recombinant protein) - Order from Adipogen Home BCMA (mouse):Fc (human) (rec.) BCMA (mouse):Fc (human) (rec.) AG-40B-0076-C050 50 µg CHF 240.00 AG-40B-0076-3050 3 x 50 µg CHF 480.00 Size Qty Add to Cart Contact Us! Specifications / Handling Description
Web9 May 2024 · Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold Chimeric antigen receptor (CAR)-T cells have demonstrated significant clinical potential; however, their strong antitumor activity may cause severe adverse effects.
Web27 May 2024 · In this issue of Blood, Wang et al report their phase 1 trial of CT103, a fully human 4-1BBζ chimeric antigen receptor (CAR) targeting the B-cell maturation antigen (BCMA), in 18 patients with relapsed or refractory multiple myeloma (MM). 1 hermitage learning center hermitage tnB-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). hermitage ledgestoneWeb maxfreight internationalWeb5 Feb 2024 · B-cell maturation antigen (BCMA), a cell surface receptor recognizing B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL), play an important role in the survival of long-lived PCs in the bone marrow ( 14–17 ). BCMA is expressed on PCs and is highly expressed on myeloma cells while being absent on most other cells ( 18 ). hermitage learning centerWebCD269, also known as B cell maturation antigen (BCMA), is a 27 kD, single pass transmembrane protein with one TNFR-Cys repeat on its extracellular domain. CD269 is … max freight virturalWeb14 Apr 2024 · Abstract. Background: The introduction of novel targeted therapies and immunotherapies has dramatically improved responses and overall survival in multiple … hermitage law hermitage paWebThe present invention relates to novel human CD3 antigen-binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also relates to bispecific antibo maxfreight international logistics inc