Web26 de fev. de 2024 · HIF1A driven transcriptional response in hypoxia depends on epigenetic control at DNA methylation status of gene regulatory regions. Furthermore, … WebGene summary (Entrez)i. Useful information about the gene from Entrez. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer c omposed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating ...
HIF1A protein expression summary - The Human Protein Atlas
Web1 de jul. de 2009 · MXI1 was also rapidly induced by hypoxia in cultured breast carcinoma cells, indicating a general and important role of MXI1 in adjustment to hypoxic conditions. MXI1 protein was present in both neuroblastoma and DCIS specimens, and high MXI1 immunoreactivity correlated to high HIF-1α levels in neuroblastoma. In summary we … WebIt is demonstrated that upregulation of HIF-1 α in NB promotes proliferation, migration and invasiveness via SHH signaling and the pro-migration and proliferative effects of Hif-1α could be reversed by disrupting SHH signalling. The aim of this study was to investigate the effects of hypoxia-inducible factor-1α (HIF-1α) on the proliferation, migration and … income based job seekers
Hypoxia-inducible factor (HIF-1) α: its protein stability and ...
WebHypoxia-Inducible Factor-1 (HIF-1 ) in SK-N-BE(2)C Neuroblastoma Cells Seolhyun PARK,1;* Yoo-Sun KIM,1;* Hyun-Ah LEE,1 Yunsook LIM,2 and Yuri KIM1;y 1Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 120-750, Republic of Korea 2Department of Food and Nutrition, Kyung Hee University, Seoul 130 … Web8 de nov. de 2016 · HIF-1α expression was negatively correlated with cell proliferation in the linc01105 KD group. In addition, Noxa and Bid expression was positively correlated with cell apoptosis. Moreover,... Webmalian development. HIF-1 consists of a consti-tutively expressed HIF-1β subunit and one of three subunits (HIF-1α, HIF-2α or HIF-3α). The stability and activity of HIF-1α are regulated by ... income based jobseeker\\u0027s allowance uk